Police are investigating a fatal stabbing that occurred in broad daylight in the South of Market neighborhood Friday.

A female construction worker was reportedly stabbed in front of Harvey’s Place liquor store at 330 5th St., according to police. The victim was taken to the hospital, where she succumbed to her injuries.

Streets remained closed in the area of Fifth and Folsom streets, and Fifth and Harrison streets as of 12:30 p.m.

Police said tow suspects were detained at the scene.

Around 1:30 p.m. the crime scene had been dismantled and fire crews arrived to wash away blood from the sidewalk in front of Harvey’s Place.

Harvey’s Place owner Muhammad Malik, 54, did not witness the stabbing, but said that vagrancy around the area has been a problem for some time.

“Homeless always,” he said.

The worker who was killed was flagging traffic for a Cahill Contractors construction project around the corner down narrow Shipley Street.

Cahill Contractors Vice President Gui Estes said the victim was the employee of a subcontractor working on an apartment building on Shipley Street between Fifth and Falmouth streets.

The victim, said Estes, was an employee of Dees Hennessy, a San Carlos-based company that was doing concrete work at the site, which has been closed for the day because of the killing.

“This is the most extreme thing we’ve seen happen,” said Estes of Friday’s killing. “It’s a tragedy and our hearts go out to the victim’s family.

Dees Hennessy has not returned a call for comment.

Meanwhile, Mayor Ed Lee released a statement on the killing late Friday.

“On behalf of the City and County of San Francisco, I extend my deepest condolences to the family of the victim who died after being stabbed. Our thoughts and prayers remain with her family, friends and colleagues during this time of mourning and sorrow. The victim was a 2013 graduate of the CityBuild program and a proud member of Laborers’ Local 261,” Lee’s statement said.

The killing, if it’s classified a homicide, will mark The City’s 22 of 2016.

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A female construction worker was fatally stabbed on Friday outside Harvey's Place liquor store in SoMa, according to police. (Jessica Christian/S.F. Examiner)