Cindy Chew/2004 S.F. Examiner file photoTwo people were critically injured in a fire in the North of Panhandle area on Wednesday night.

Two residents critically injured in 3-alarm NoPa fire

A three-alarm fire at an apartment building in San Francisco's North of Panhandle neighborhood on Wednesday night sent two residents to the hospital with life-threatening injuries, a fire spokeswoman said.

The fire was reported at 8:52 p.m. at a four-story building at 618 Baker St.

Crews initially had trouble accessing the roof because it was obstructed by wires. They eventually reached the roof and opened it up to ventilate the blaze, fire department spokeswoman Mindy Talmadge said. The fire was controlled at 9:39 p.m.

Two adults were critically injured in the fire and are being treated at a hospital this morning for serious burn wounds, she said.

The blaze, which remains under investigation, caused an estimated $350,000 in damage to the building and destroyed $150,000 worth of contents, Talmadge said.

More than 100 firefighters responded to the fire, and some crews monitored the site overnight, Talmadge said.

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