A man suffered life-threatening injuries in a hit-and-collision in San Francisco’s South of Market neighborhood on Wednesday afternoon, police said.

The collision was reported at 3:16 p.m. in the area of Seventh and Natoma streets.

The 27-year-old victim was taken to a hospital to be treated for his injuries.

The driver, a man believed to be between 25 and 30 years old, left his vehicle and fled the area on foot. He remains at large and police did not immediately release a detailed description.