Looking for something to do after work today? We've sifted through the listings for you. Here are your best bets, starting with our top pick, a sing-along version of “Grease” at the Castro Theatre.

Back to the 1950s

“Sing-A-Long Grease,” the interactive version of the 1978 musical film, continues through Wednesday at the Castro Theatre. A “Grease” costume contest also is on the bill. [8 p.m., 429 Castro St.]

Who’s in town

Moira Gunn, host of the public-radio programs “Tech Nation” and “BioTech Nation,” gives a talk titled “The Five Biggest Biotech Challenges Facing America.” [6 p.m., Commonwealth Club, 595 Market St.]

City activities

Apple crop: Apple Worldwide Developers Conference opens. Developers and IT professionals from around the globe come together. Steve Jobs gives the keynote speech. [7 a.m. to 7 p.m., Moscone Center West, 747 Howard St.]

Bar talk: Intersection for the Arts continues its “Prison Project” series, which features conversations and performances that explore California’s prison system. [7 p.m., Intersection for the Arts, 446 Valencia St.]

Literary events

Philip Zimbardo: The psychologist and author discusses “The Lucifer Effect.” [5:15 p.m., Commonwealth Club, 595 Market St.]

Left Coast Writers: Group members read from their work. “Hittingthe Road” is the program’s theme. [5:30 p.m., Book Passage, 1 Ferry Plaza]

Lectures

Tom Kundig: The award-winning architect appears in conversation. [5:30 to 7:30 p.m., AIA SF + AIGA SF, 130 Sutter St., Suite 600]

Jordan Essoe: The artist discusses his new painting and video work focusing on the Israeli-Palestinian conflict. Judah L. Magnes Museum curator Alla Efimova joins him. [7:30 p.m., Modern Times Bookstore, 888 Valencia St.]