Guard Avry Holmes became the latest player to decide to transfer from USF on Thursday. Holmes started all 33 games and averaged 12.5 points per game this past year.
"Although I'm disappointed in [Avry's] decision, we as a staff and team want him to find what he is looking for and wish him nothing but the best in the future," USF coach Rex Walters said in a statement.
USF finished the 2013-14 season with a 13-5 conference record, its most conference wins since 1976-77.
Players bolting the Hilltop has become a bit of an alarming trend.
Starting guard Cody Doolin left in the middle of this past season after a reported altercation with a teammate. After the 2011-12 season, six players transferred from USF.
"The goal for us is to continue to improve our infrastructure to provide our student-athletes with everything they need to be successful on a high level," USF athletic director Scott Sidwell said.
Meanwhile across the Bay, Cal junior guard Ricky Kreklow will transfer, the Bay Area News Group reported. Kreklow missed a combined 35 games over the past two seasons.